![]() Several studies have presented good reproducibility of OCT retinal thickness measurements and have shown that it is currently the most precise and reliable instrument for retinal thickness measurements. As clinicians are becoming increasingly reliant on OCT retinal thickness measurements, it is important to determine their accuracy. OCT is now an integral part of both retinal clinical practice and many clinical trials. Owing to its ability to quantify changes in retinal thickness, OCT has become an indispensable tool for assessing treatment initiation, the response to treatment and the need for retreatment in many retinal diseases. 2–5 OCT is also a powerful method for obtaining retinal thickness measurements. It is a fast, non-invasive, non-contact method that enables in vivo visualisation of the retinal and vitreoretinal microstructure on a high-resolution cross-section (2D) or 3D image. Optical coherence tomography (OCT) was introduced by Huang and colleauges in 1991 1 and became commercially available in 1995. Optical coherence tomography, retinal thickness measurements, segmentation break-down Article: The awareness of the clinician and the particular search for, and recognition of, measurement errors would improve the accuracy of OCT interpretation and should be an integral part of OCT scan analysis. pigment epithelial detachment, subretinal fluid, fibrotic tissue, hard exudates and full-thickness macular holes). ‘out-of-range’, mirror, blink and motion artefacts), a low signal:noise ratio, dense media opacities and specific retinal pathological features (e.g. The segmentation software might perform less accurately in the presence of scan artefacts (e.g. In this review, the author describes and discusses the various causes that might compromise automated retinal thickness measurements. However, as with any imaging technology, some limitations exist. This review provides a toolkit for successful image interpretation in a clinical setting.Optical coherence tomography (OCT) has become an indispensable tool in the assessment of macular pathology in clinical settings and an integral part of many clinical trials. Conclusion OCTA is evolving from a scientific tool to a clinical imaging device. Lastly, the use of OCTA for the clinical interpretation of retinal pathology, such as diabetic retinopathy and age-related macular degeneration, is discussed. Slabs offered in standard OCTA devices are reviewed, and clinical uses for each slab are outlined. OCTA has the unique ability among retinovascular imaging modalities to individually visualize each retinal plexus. New methods and best practices to prevent image artifacts are discussed. The review begins with a summary of OCTA technology and artifacts that arise from image acquisition. Body This review provides an overview of OCTA imaging and details tips for successful interpretation. ![]() While countless publications detail OCTA's use for the study of retinal microvasculature, few studies outline OCTA's clinical utility. Over time, more clinical practices have adopted OCTA imaging. This technology has been commercially available since 2014, however, much of its use has been limited to the research setting. Abstract : Background Optical coherence tomography angiography (OCTA) can image the retinal vasculature in vivo, without the need for contrast dye.
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